Investing in Innovation (i3) is a pan-African initiative that supports the commercialization and impact of promising early- and growth-stage startups through grants, introductions to major healthcare organizations, and market access support. It focuses on health tech innovations addressing product distribution challenges in African healthcare systems. From September 2022 to April 2025, i3 participated in 9 funding rounds totaling $625K, primarily in other stages (8 rounds) and one seed round. Investments targeted health tech (7 companies), with additional focus on cybersecurity (1) and fintech (1). Geographic preferences include Nigeria (4), Kenya (2), South Africa (1), Uganda (1), and Cameroon (1). Backed companies include Sproxil, Biocertica, Tibu Health, PharmaServ, SASAdoctor, Drugstoc, clinicPesa, OneHealth, and Infiuss Health. i3 provides risk-tolerant funding such as $50K grants for early-stage innovators and up to $225K for growth-stage ones, alongside bespoke deal facilitation and customer introductions to drive adoption and scale.