E Squared Investments is a South African investment firm that supports high-growth businesses, fund managers, and social enterprises. Operating as E2 Investments Proprietary Limited, a subsidiary of EΒ² Trust, it is based in Bryanston, Johannesburg. The firm provides institutional capital, commercial discipline, and strategic support to entrepreneurs and management teams. E Squared invests across various stages, including seed and growth-stage funding for scalable businesses. It has backed three South African companies: Mynextcar in Travel & Mobility with a $10.0M venture round in June 2025, Khula in Agri Tech with a $6.7M Series A in March 2025, and LocumBase in Health Tech with debt financing in December 2020. Total investments amount to $16.7M from December 2020 to June 2025, with co-investors including Emso Asset Management, Assemble49-Global, Bolt, AECI, PepsiCo South Africa, Absa Bank, and Jozi Angels. The firm emphasizes long-term financial and social returns, particularly through programs like the 2V investment for Allan Gray Fellow-run ventures and support for youth-focused social enterprises.