Polychain Capital is a venture capital firm focused on cryptocurrency and blockchain technology. The firm invests in blockchain-based digital assets through actively managed portfolios. It is based in San Francisco, California. Polychain Capital has demonstrated interest in Pan-African opportunities within the Crypto & Web3 sector. From August 2020 to October 2024, it participated in three funding rounds totaling $74.5M, spanning Seed, Series B, and Series C stages. All investments targeted Yellowcard, a stablecoin and fiat payments infrastructure provider for emerging markets. The firm has co-invested alongside notable partners including Third Prime Capital, Castle Island Ventures, and Blockchain Capital across these rounds.